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A single precise strike to the right location is enough to disrupt most commercial heart monitors. Fortunately, the calculations involved in finding that location are beyond normal human cognition.
This is a generally available augment that allows the agent's attacks ignore heart monitors, at a cost of 3 PWR per attack. This allows an agent to kill guards without raising the alarm but it also allows an agent to KO guards on Expert Plus, Endless Plus, or any time the “Alarm when guards KO” difficulty setting is switched on. This augment has no effect on cleanup cost.